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Literature summary for 2.3.1.32 extracted from
- Enzyme synthesis of epsilon-N-acetyl-L-lysine (1964), Arch. Biochem. Biophys., 108, 221-229.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no inhibition by cysteine, glutathione, ascorbic acid, Zn2+, Mn2+, Co2+, Ni2+, Fe3+ or acetate | Bos taurus | |
| phosphate | above 0.1 mM | Bos taurus |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.32 | - |
L-ornithine | - |
Bos taurus | |
| 1.35 | - |
acetyl phosphate | cosubstrate L-ornithine | Bos taurus | |
| 4.24 | - |
L-lysine | - |
Bos taurus | |
| 12.4 | - |
acetyl phosphate | cosubstrate L-lysine | Bos taurus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | slight stimulation | Bos taurus | |
| Mg2+ | slight stimulation | Bos taurus | |
| additional information | no activation by Zn2+, Mn2+, Co2+, Ni2+, Fe3+ or acetate | Bos taurus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl phosphate + L-lysine | Bos taurus | - |
phosphate + N6-acetyl-L-lysine | - |
? | |
| acetyl phosphate + L-ornithine | Bos taurus | best substrate | phosphate + N5-acetyl-L-ornithine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 1.43 | - |
- |
Bos taurus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 0°C, 5 h | Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl phosphate + L-lysine | - |
Bos taurus | phosphate + N6-acetyl-L-lysine | - |
? | |
| acetyl phosphate + L-ornithine | best substrate | Bos taurus | phosphate + N5-acetyl-L-ornithine | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 38 | - |
assay at | Bos taurus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.6 | - |
various buffer systems | Bos taurus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 8.3 | 9.2 | about half-maximal activity at pH 8.3, about 70% of maximal activity at pH 9.2 | Bos taurus |
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Release 2023.1 (January 2023)
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