Cloned (Comment) | Organism |
---|---|
expression as glutathione-S-transferase fusion protein, amino acid sequence | Trypanosoma cruzi |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D-cysteine | no inhibition | Trypanosoma cruzi | |
glutathione | weak, allosteric inhibition | Trypanosoma cruzi | |
L-cysteine | allosteric inhibition | Trypanosoma cruzi | |
L-cystine | allosteric inhibition | Trypanosoma cruzi | |
L-homocysteine | weak | Trypanosoma cruzi | |
L-homoserine | weak | Trypanosoma cruzi | |
N-acetyl-L-cysteine | weak | Trypanosoma cruzi |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.24 | - |
L-serine | - |
Trypanosoma cruzi | |
0.92 | - |
acetyl-CoA | - |
Trypanosoma cruzi |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
38400 | - |
x * 38400, amino acid sequence determination | Trypanosoma cruzi |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + L-serine | Trypanosoma cruzi | key role in the sulfur assimilatory pathway | CoA + O-acetyl-L-serine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma cruzi | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + L-serine | - |
Trypanosoma cruzi | CoA + O-acetyl-L-serine | - |
? | |
acetyl-CoA + L-serine | key role in the sulfur assimilatory pathway | Trypanosoma cruzi | CoA + O-acetyl-L-serine | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 38400, amino acid sequence determination | Trypanosoma cruzi |
Synonyms | Comment | Organism |
---|---|---|
SAT | - |
Trypanosoma cruzi |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.012 | - |
L-cysteine | versus L-serine | Trypanosoma cruzi | |
0.14 | - |
L-cysteine | versus acetyl-CoA | Trypanosoma cruzi |