Literature summary for 2.3.1.262 extracted from

Hinsberger, S.; de Jong, J.C.; Groh, M.; Haupenthal, J.; Hartmann, R.W.
Benzamidobenzoic acids as potent PqsD inhibitors for the treatment of Pseudomonas aeruginosa infections (2014), Eur. J. Med. Chem., 76, 343-351.

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Inhibitors

Inhibitors	Comment	Organism	Structure
2-[(biphenyl-4-ylcarbonyl)amino]-3-chlorobenzoic acid	strong inhibition, without inhibiting RNA polymerase	Pseudomonas aeruginosa

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas aeruginosa	-	-	-

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0062	-	pH not specified in the publication, temperature not specified in the publication	Pseudomonas aeruginosa	2-[(biphenyl-4-ylcarbonyl)amino]-3-chlorobenzoic acid

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Release 2023.1 (January 2023)