Literature summary for 2.3.1.260 extracted from

Zhang, W.; Ames, B.D.; Tsai, S.C.; Tang, Y.
Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase (2006), Appl. Environ. Microbiol., 72, 2573-2580.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
malonamoyl-[OxyC acyl-carrier protein] + malonyl-CoA	Streptomyces rimosus	-	18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC acyl-carrier protein] + CO2 + CoA	-	?
malonamoyl-[OxyC acyl-carrier protein] + malonyl-CoA	Streptomyces rimosus CH999	-	18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC acyl-carrier protein] + CO2 + CoA	-	?

Organism

Organism	UniProt	Comment	Textmining
Streptomyces rimosus	-	-	-
Streptomyces rimosus CH999	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
malonamoyl-[OxyC acyl-carrier protein] + malonyl-CoA	-	Streptomyces rimosus	18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC acyl-carrier protein] + CO2 + CoA	-	?
malonamoyl-[OxyC acyl-carrier protein] + malonyl-CoA	-	Streptomyces rimosus CH999	18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC acyl-carrier protein] + CO2 + CoA	-	?

Synonyms

Synonyms	Comment	Organism
oxy	-	Streptomyces rimosus
OxyA	-	Streptomyces rimosus
OxyB	-	Streptomyces rimosus
OxyC	-	Streptomyces rimosus
oxytetracycline PKS	-	Streptomyces rimosus
oxytetracycline polyketide synthase	-	Streptomyces rimosus

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Release 2023.1 (January 2023)