Activating Compound | Comment | Organism | Structure |
---|---|---|---|
25-hydroxycholesterol | stimulates enzyme activity in liver microsomes in vitro with half-maximal stimulation at 0.0168 mM oxysterol. A major part of the activation of microsomal enzyme is not ascribable to increased substrate availability for the enzyme | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male Wistar strain | - |
Rattus norvegicus male Wistar | - |
male Wistar strain | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0000582 | - |
microsomal fraction without 25-hydroycholesterol | Rattus norvegicus |
0.0000982 | - |
microsomal fraction with 25-hydroycholesterol | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
oleoyl-CoA + cholesterol | - |
Rattus norvegicus | CoA + cholesteryl oleate | - |
? | |
oleoyl-CoA + cholesterol | - |
Rattus norvegicus male Wistar | CoA + cholesteryl oleate | - |
? |