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Literature summary for 2.3.1.245 extracted from

  • Marques, J.C.; Oh, I.K.; Ly, D.C.; Lamosa, P.; Ventura, M.R.; Miller, S.T.; Xavier, K.B.
    LsrF, a coenzyme A-dependent thiolase, catalyzes the terminal step in processing the quorum sensing signal autoinducer-2 (2014), Proc. Natl. Acad. Sci. USA, 111, 14235-14240.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.245

Crystallization (Commentary)

Crystallization (Comment) Organism
crystals of the catalytically inactive mutant enzyme K203A Escherichia coli

Protein Variants

Protein Variants Comment Organism
K203A inactive mutant enzyme Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-hydroxy-5-phosphonooxypentane-2,4-dione + coenzyme A Escherichia coli the enzyme participates in a degradation pathway of the bacterial quorum-sensing autoinducer molecule AI-2 i.e. (S)-4,5-dihydroxypentane-2,3-dione glycerone phosphate + acetyl-CoA
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 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli P76143
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxy-5-phosphonooxypentane-2,4-dione + coenzyme A
-
 Escherichia coli glycerone phosphate + acetyl-CoA
-
 ?
3-hydroxy-5-phosphonooxypentane-2,4-dione + coenzyme A the enzyme participates in a degradation pathway of the bacterial quorum-sensing autoinducer molecule AI-2 i.e. (S)-4,5-dihydroxypentane-2,3-dione Escherichia coli glycerone phosphate + acetyl-CoA
-
 ?

General Information

General Information Comment Organism
metabolism the enzyme participates in a degradation pathway of the bacterial quorum-sensing autoinducer molecule AI-2 Escherichia coli