Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-Bromopalmitate | specific inhibitor for protein palmitoylation. Treatment compromises root hair elongation and polarity; specific inhibitor for protein palmitoylation. Treatment compromises root hair elongation and polarity | Arabidopsis thaliana |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
Golgi apparatus | - |
Arabidopsis thaliana | 5794 | - |
tonoplast | - |
Arabidopsis thaliana | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | Q52T38 | - |
- |
Arabidopsis thaliana | Q7XA86 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
root hair | - |
Arabidopsis thaliana | - |
Synonyms | Comment | Organism |
---|---|---|
PAT10 | - |
Arabidopsis thaliana |
PAT24 | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
physiological function | isoform PAT10 plays a secondary role in root hair growth. Treatment with palmitoylation-specific inhibitor 2-bromopalmitate compromises root hair elongation and polarity and impairs the dynamic polymerization of actin microfilaments, the asymmetric plasma membrane localization of phosphatidylinositol (4,5)-bisphosphate, the dynamic distribution of RabA4b-positive post-Golgi secretion, and endocytic trafficking in root hairs | Arabidopsis thaliana |
physiological function | protein palmitoylation, contributed primarily by the Golgi-localized isoform TIP1 and secondarily by protein S-acyl transferases from other endomembrane compartments, plays a key role in the polar growth of root hairs. Treatment with specific inhibitor 2-bromopalmitate compromises root hair elongation and polarity and impairs the dynamic polymerization of actin microfilaments, the asymmetric plasma membrane localization of phosphatidylinositol (4,5)-bisphosphate, the dynamic distribution of RabA4b-positive post-Golgi secretion, and endocytic trafficking in root hairs | Arabidopsis thaliana |