Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cardiolipin | inhibits conversion of palmitoylcarnitine to palmitoyl-CoA, stimulates palmitoylcarnitine formation | Rattus norvegicus | |
palmitoylcarnitine | high above micellar concentrations increase conversion of palmitoylcarnitine to palmitoyl-CoA by facilitating the removal of palmitoyl-CoA from the enzyme surface | Rattus norvegicus | |
Phosphatidylcholine liposomes | high above micellar concentrations increase conversion of palmitoylcarnitine to palmitoyl-CoA by facilitating the removal of palmitoyl-CoA from the enzyme surface | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cardiolipin | inhibits conversion of palmitoylcarnitine to palmitoyl-CoA, stimulates palmitoylcarnitine formation | Rattus norvegicus | |
palmitoyl-CoA | product inhibition, reverse reaction | Rattus norvegicus | |
phosphatidylcholine | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
KCl | high above micellar concentrations increase conversion of palmitoylcarnitine to palmitoyl-CoA by facilitating the removal of palmitoyl-CoA from the enzyme surface | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + L-carnitine | Rattus norvegicus | - |
CoA + L-acylcarnitine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
liver mitochondria | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
24 | - |
purified enzyme | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + L-carnitine | - |
Rattus norvegicus | CoA + L-acylcarnitine | - |
? | |
palmitoyl-CoA + L-carnitine | - |
Rattus norvegicus | CoA + L-palmitoylcarnitine | - |
r |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Rattus norvegicus |