Cloned (Comment) | Organism |
---|---|
expressed in HEK-293 cells | Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0085 | - |
11-cis-retinol | at pH 8.0 and 37°C | Mus musculus | |
0.0099 | - |
all-trans-retinol | at pH 8.0 and 37°C | Mus musculus | |
0.0188 | - |
13-cis-retinol | at pH 8.0 and 37°C | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
45000 | - |
x * 45000, SDS-PAGE | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Mueller glial cell | - |
Mus musculus | - |
retina | - |
Mus musculus | - |
retinal pigment epithelium cell | - |
Mus musculus | - |
RPE cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
palmitoyl-CoA + 11-cis-retinol | - |
Mus musculus | ? | - |
? | |
palmitoyl-CoA + 13-cis-retinol | - |
Mus musculus | ? | - |
? | |
palmitoyl-CoA + all-trans-retinol | - |
Mus musculus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 45000, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
DGAT1 | - |
Mus musculus |
diacylglycerol O-acyltransferase type-1 | - |
Mus musculus |
diacylglycerol O-acyltransferase-1 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme-deficient mice show no effect on retinal anatomy or the ultrastructure of photoreceptor outer-segments. Enzyme loss affects retinyl-ester synthesis and total acyl-coenzyme A:retinol acyl-transferase activityin the eye | Mus musculus |