Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | tgs transcript levels are upregulated under various stress culture conditions | Mycobacterium tuberculosis |
Application | Comment | Organism |
---|---|---|
drug development | the enzyme is a possible target for antilatency drugs | Mycobacterium tuberculosis |
Cloned (Comment) | Organism |
---|---|
gene tgs1, expressionin Escherichia coli, the recombinant enzyme prefers C26 : 0-CoA for triglycerol accumulation | Mycobacterium tuberculosis |
Protein Variants | Comment | Organism |
---|---|---|
additional information | disruption of gene tgs1, i.e. Rv3130c, leads to drastically reduced triacylglycerol accumulation | Mycobacterium tuberculosis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Mycobacterium tuberculosis | - |
strain ATCC 25618, gene tgs1 or Rv3130c | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
diolein + hexacosanoyl-CoA | - |
Mycobacterium tuberculosis | ? | - |
? | |
diolein + oleoyl-CoA | - |
Mycobacterium tuberculosis | triolein + CoA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
diacylglycerol acyltransferase | - |
Mycobacterium tuberculosis |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Mycobacterium tuberculosis |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
assay at | Mycobacterium tuberculosis |