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Literature summary for 2.3.1.168 extracted from

  • Lau, K.S.; Herring, W.J.; Chuang, J.L.; McKean, M.; Danner, D.J.; Cox, R.P.; Chuang, D.T.
    Structure of the gene encoding dihydrolipoyl transacylase (E2) component of human branched chain alpha-keto acid dehydrogenase complex and characterization of an E2 pseudogene (1992), J. Biol. Chem., 267, 24090-24096.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene contains a mitochondrial targeting presequence Homo sapiens
gene E2, DNA sequence determination and analysis Homo sapiens
pseudogene E2, DNA sequence determination and analysis, retroposon, gene corresponds to the complete mitochondrial presequence and the lipoyl-bearing domain encoded by exon I through IV of the functional gene E2 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
-

Organism

Organism UniProt Comment Textmining
Homo sapiens P11182 gene E2
-
Homo sapiens P11182 pseudogene E2
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
Homo sapiens
-
kidney
-
Homo sapiens
-
lymphoblast
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
-
Homo sapiens CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
?

Synonyms

Synonyms Comment Organism
More enzyme is the E2 component of the multienzyme complex branched-chain alpha-keto acid dehydrogenase, i.e. branched-chain 2-oxo acid dehydrogenase Homo sapiens