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Literature summary for 2.3.1.16 extracted from
- 3-Ketoacyl-CoA thiolase of mammalian tissues (1975), Methods Enzymol., 35 B, 128-136.
No PubMed abstract available
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.01 | - |
acetoacetyl-CoA | - |
Rattus norvegicus |  |
| 0.018 | - |
CoA | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
| mitochondrion | - |
Sus scrofa | 5739 | - |
| mitochondrion | - |
Bos taurus | 5739 | - |
| mitochondrion | - |
Ovis aries | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Ovis aries | - |
male | - |
| Rattus norvegicus | - |
- |
- |
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| general method for separation, quantitation and partial purification | Bos taurus |
| general method for separation, quantitation and partial purification | Ovis aries |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| heart | - |
Rattus norvegicus | - |
| heart | - |
Sus scrofa | - |
| heart | - |
Bos taurus | - |
| kidney | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
| liver | - |
Sus scrofa | - |
| liver | - |
Bos taurus | - |
| semen | - |
Ovis aries | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, glycerol, several weeks | Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CoA + 3-oxoacyl-CoA | - |
Rattus norvegicus | acyl-CoA + acetyl-CoA | - |
r | |
| CoA + 3-oxoacyl-CoA | - |
Sus scrofa | acyl-CoA + acetyl-CoA | - |
r | |
| CoA + 3-oxoacyl-CoA | - |
Bos taurus | acyl-CoA + acetyl-CoA | - |
r | |
| CoA + 3-oxoacyl-CoA | - |
Ovis aries | acyl-CoA + acetyl-CoA | - |
? | |
| CoA + 3-oxohexanoyl-CoA | highest activity with 3-oxohexanoyl-CoA | Rattus norvegicus | acetyl-CoA + butanoyl-CoA | - |
r | |
| CoA + 3-oxohexanoyl-CoA | highest activity with 3-oxohexanoyl-CoA | Sus scrofa | acetyl-CoA + butanoyl-CoA | - |
r | |
| CoA + 3-oxohexanoyl-CoA | highest activity with 3-oxohexanoyl-CoA | Bos taurus | acetyl-CoA + butanoyl-CoA | - |
r | |
| CoA + 3-oxohexanoyl-CoA | highest activity with 3-oxohexanoyl-CoA | Ovis aries | acetyl-CoA + butanoyl-CoA | - |
? | |
| CoA + 3-oxopalmitoyl-CoA | - |
Rattus norvegicus | acetyl-CoA + tetradecanoyl-CoA | - |
? | |
| CoA + 3-oxopalmitoyl-CoA | - |
Sus scrofa | acetyl-CoA + tetradecanoyl-CoA | - |
? | |
| CoA + 3-oxopalmitoyl-CoA | - |
Bos taurus | acetyl-CoA + tetradecanoyl-CoA | - |
? | |
| CoA + acetoacetyl-CoA | - |
Rattus norvegicus | acetyl-CoA + acetyl-CoA | - |
r | |
| CoA + acetoacetyl-CoA | - |
Sus scrofa | acetyl-CoA + acetyl-CoA | - |
r | |
| CoA + acetoacetyl-CoA | - |
Bos taurus | acetyl-CoA + acetyl-CoA | - |
r | |
| additional information | 3-oxoacyl-CoA homologues from acetoacetyl to 3-oxopalmitoyl-CoA | Rattus norvegicus | ? | - |
? | |
| additional information | 3-oxoacyl-CoA homologues from acetoacetyl to 3-oxopalmitoyl-CoA | Sus scrofa | ? | - |
? | |
| additional information | 3-oxoacyl-CoA homologues from acetoacetyl to 3-oxopalmitoyl-CoA | Bos taurus | ? | - |
? | |
| additional information | 3-oxoacyl-CoA homologues from acetoacetyl to 3-oxopalmitoyl-CoA | Ovis aries | ? | - |
? | |
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Release 2023.1 (January 2023)
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