Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Polymyxin B | activation of mitochondrial enzyme, inhibition of microsomal enzyme | Rattus norvegicus |
General Stability | Organism |
---|---|
phospholipids stabilize | Escherichia coli |
phospholipids stabilize | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5,5'-dithiobis(2-nitro-benzoate) | - |
Escherichia coli | |
5,5'-dithiobis(2-nitro-benzoate) | inhibition of microsomal enzyme, mitochondrial enzyme is not inhibited | Rattus norvegicus | |
acetone | inhibition of microsomal enzyme | Rattus norvegicus | |
iodoacetamide | strong inhibition of microsomal enzyme, mitochondrial enzyme is not inhibited | Rattus norvegicus | |
MgCl2 | inhibition of microsomal enzyme | Rattus norvegicus | |
N-ethylmaleimide | - |
Escherichia coli | |
N-ethylmaleimide | strong inhibition of microsomal isozyme, mitochondrial enzyme is not inhibited | Rattus norvegicus | |
Polymyxin B | 0.5 mg/ml, approx. 75% inhibition of microsomal enzyme, slight stimulation of mitochondrial enzyme | Rattus norvegicus | |
Triton X-100 | - |
Escherichia coli | |
Triton X-100 | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | membrane-bound | Rattus norvegicus | - |
- |
mitochondrial membrane | membrane-bound | Rattus norvegicus | 31966 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | activity of microsomal enzyme is probably regulated by phosphorylation-dephosphorylation | Rattus norvegicus |
Purification (Comment) | Organism |
---|---|
Triton X-100-solubilized | Escherichia coli |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
mammary gland | lactating | Rattus norvegicus | - |
additional information | distribution, overview | Escherichia coli | - |
additional information | distribution, overview | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + sn-glycerol 3-phosphate | saturated acyl-CoAs preferred | Escherichia coli | CoA + 1-acyl-sn-glycerol 3-phosphate | - |
? | |
acyl-CoA + sn-glycerol 3-phosphate | saturated acyl-CoAs preferred | Rattus norvegicus | CoA + 1-acyl-sn-glycerol 3-phosphate | - |
? |