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Literature summary for 2.3.1.13 extracted from

  • van der Sluis, R.; Ungerer, V.; Nortje, C.; A van Dijk, A.; Erasmus, E.
    New insights into the catalytic mechanism of human glycine N-acyltransferase (2017), J. Biochem. Mol. Toxicol., 31, e21963 .
    View publication on PubMed
Search for more literature for 2.3.1.13

Application

Application Comment Organism
analysis determination of kinetic parameters of recombinant human enzyme using the traditional colorimetric method and a HPLC-ESI-MS/MSmethod Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.189
-
 glycine K0.5 value at 0.02 mM benzoyl-CoA, pH 8.0, temperature not specified in the publication Homo sapiens
2.326
-
 glycine K0.5 value at 0.04 mM benzoyl-CoA, pH 8.0, temperature not specified in the publication Homo sapiens
2.956
-
 glycine K0.5 value at 0.08 mM benzoyl-CoA, pH 8.0, temperature not specified in the publication Homo sapiens
30.42
-
 benzoyl-CoA K0.5 value at 2.5 mM gylcine, pH 8.0, temperature not specified in the publication Homo sapiens
108.3
-
 benzoyl-CoA K0.5 value at 5 mM gylcine, pH 8.0, temperature not specified in the publication Homo sapiens
305
-
 benzoyl-CoA K0.5 value at 20 mM gylcine, pH 8.0, temperature not specified in the publication Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q6IB77
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzoyl-CoA + glycine
-
 Homo sapiens CoA + N-benzoylglycine
-
 ?
additional information GLYAT exhibits mechanistic kinetic cooperativity Homo sapiens ?
-
-

Synonyms

Synonyms Comment Organism
GlyAT
-
 Homo sapiens