Activating Compound | Comment | Organism | Structure |
---|---|---|---|
bovine serum albumin | activation, molar ratio substrate linoleoyl-CoA/albumin: 2:4:1 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-O-Hexadecyl-2-oleoyl-sn-glycerol | competitive inhibitor of 1-hexadecyl-2-acetyl-3-acyl-sn-glycerol synthesis | Homo sapiens | |
1-oleoyl-2-acetyl-sn-glycerol | mixed-type inhibition | Homo sapiens | |
Ca2+ | 6% inhibition at 2 mM | Homo sapiens | |
Cu2+ | 96% inhibition at 2 mM | Homo sapiens | |
dithiothreitol | - |
Homo sapiens | |
Mn2+ | 35% inhibition at 2 mM | Homo sapiens | |
Zn2+ | 93% inhibition at 2 mM | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0085 | - |
linoleoyl-CoA | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | no metal ion requirement | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | related to platelet-activating factor metabolism | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HL-60 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
linoleoyl-CoA + 1-O-hexadecyl-2-acetyl-sn-glycerol | best substrate, not acetyl-CoA | Homo sapiens | CoA + 1-O-hexadecyl-2-acetyl-3-linoleoyl-sn-glycerol | - |
? | |
additional information | related to platelet-activating factor metabolism | Homo sapiens | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
45 | - |
stable below | Homo sapiens |
58 | - |
50% activity after 15 min | Homo sapiens |
65 | - |
inactivation | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.8 | - |
- |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.032 | - |
1-O-Hexadecyl-2-oleoyl-sn-glycerol | - |
Homo sapiens |