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Literature summary for 2.3.1.108 extracted from

  • Kalebic, N.; Sorrentino, S.; Perlas, E.; Bolasco, G.; Martinez, C.; Heppenstall, P.
    alphaTAT1 is the major alpha-tubulin acetyltransferase in mice (2013), Nat. Commun., 4, 1962.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Mus musculus Q8K341
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-

Synonyms

Synonyms Comment Organism
ATAT1
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Mus musculus

General Information

General Information Comment Organism
physiological function mice with a targeted deletion of Atat1 display a loss of detectable K40 alpha-tubulin acetylation across multiple tissues and in cellular structures such as cilia and axons where acetylation is normally enriched. Mice are viable and develop normally, however, the absence of Atat1 impacts upon sperm motility and male mouse fertility, and increases microtubule stability Mus musculus