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Literature summary for 2.3.1.1 extracted from

  • Haskins, N.; Mumo, A.; Brown, P.H.; Tuchman, M.; Morizono, H.; Caldovic, L.
    Effect of arginine on oligomerization and stability of N-acetylglutamate synthase (2016), Sci. Rep., 6, 38711 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.1

Inhibitors

Inhibitors Comment Organism Structure
L-arginine 1 mM, complete inhibition Maricaulis maris
L-arginine 1 mM, complete inhibition Xanthomonas campestris

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Mus musculus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
263000
-
 tetrameric structure in the presence and absence of L-arginine, gel fitlration and ultracentrifugation Maricaulis maris
277000
-
 tetramer-octamer equilibrium that shifts towards tetramers upon binding of L-arginine, gel fitlration and ultracentrifugation Xanthomonas campestris
300000
-
 gel filtration Mus musculus

Organism

Organism UniProt Comment Textmining
Maricaulis maris Q0ASS9
-
-
Mus musculus Q8R4H7
-
-
Xanthomonas campestris
-
-
-

Synonyms

Synonyms Comment Organism
NAGS
-
 Xanthomonas campestris
NAGS
-
 Mus musculus
NAGS
-
 Maricaulis maris

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
additional information
-
 specific activity decreases from 20°C to 35°C Maricaulis maris
additional information
-
 specific activity decreases from 30°C to 50°C. In the presence of L-arginine, specific activity increases 1.5fold between 30°C and 45°C Mus musculus
additional information
-
 specific activity increases from 20°C to 30°C Xanthomonas campestris
50
-
 decrease in specific activity above Xanthomonas campestris

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
additional information
-
 presence of L-arginine increases thermal stability Maricaulis maris
39.26
-
 melting temperature Maricaulis maris
44.55
-
 melting temperature, presence of 1 mM L-Arg Maricaulis maris
48.6
-
 melting temperature Mus musculus
49.63
-
 melting temperature, presence of 10 mM L-Arg Maricaulis maris
50.78
-
 melting temperature, presence of 1 mM L-Arg Mus musculus
52.96
-
 melting temperature, presence of 10 mM L-Arg Mus musculus
57.87
-
 melting temperature Xanthomonas campestris