Organism | UniProt | Comment | Textmining |
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Candida albicans | - |
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- |
Saccharomyces cerevisiae | - |
- |
- |
General Information | Comment | Organism |
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physiological function | deletion of gene ilv2 encoding acetolactate synthase results in loss of viability during isoleucine and valine starvation due to 2-oxobutanoate accumulation. Rapamycin further decreases vialbility of the mutant. Recovery from starvation is influenced by the carbon source present during recovery | Saccharomyces cerevisiae |
physiological function | deletion of gene ilv2 encoding acetolactate synthase results in significant attenuation of virulence and a grater than 100fold reduction in viability after only four hours of isoleucine and valine starvation due to 2-oxobutanoate accumulation. Rapamycin increases vialbility of both ilv1 and ilv2 mutants. Recovery from starvation is influenced by the carbon source present during starvation | Candida albicans |