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Literature summary for 2.2.1.5 extracted from
- Cellular localization of alpha-ketoglutarate: glyoxylate carboligase in rat tissues (1977), Biochim. Biophys. Acta, 499, 321-328.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | exclusively | Rattus norvegicus | 5739 | - |
| mitochondrion | exclusively | Oryctolagus cuniculus | 5739 | - |
| mitochondrion | part of alpha-ketoglutarate dehydrogenase complex | Rattus norvegicus | 5739 | - |
| mitochondrion | part of alpha-ketoglutarate dehydrogenase complex | Oryctolagus cuniculus | 5739 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-oxoglutarate + glyoxylate | Rattus norvegicus | linked to citric acid cycle | ? | - |
? |  |
| 2-oxoglutarate + glyoxylate | Oryctolagus cuniculus | linked to citric acid cycle | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
rabbit | - |
| Rattus norvegicus | - |
rat | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| heart | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
| liver | - |
Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-oxoglutarate + glyoxylate | - |
Rattus norvegicus | 2-hydroxy-3-oxohexandioate + CO2 | - |
? | |
| 2-oxoglutarate + glyoxylate | - |
Oryctolagus cuniculus | 2-hydroxy-3-oxohexandioate + CO2 | - |
? | |
| 2-oxoglutarate + glyoxylate | linked to citric acid cycle | Rattus norvegicus | ? | - |
? | |
| 2-oxoglutarate + glyoxylate | linked to citric acid cycle | Oryctolagus cuniculus | ? | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
enzyme assay at | Rattus norvegicus |
| 37 | - |
enzyme assay at | Oryctolagus cuniculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | - |
enzyme assay at | Rattus norvegicus |
| 6.5 | - |
enzyme assay at | Oryctolagus cuniculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| thiamine diphosphate | - |
Rattus norvegicus | |
| thiamine diphosphate | - |
Oryctolagus cuniculus | |
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Release 2023.1 (January 2023)
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