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Literature summary for 2.2.1.1 extracted from

  • Chen, H.; Yue, J.; Yang, S.; Ding, H.; Zhao, R.; Zhang, S.
    Overexpression of transketolase-like gene 1 is associated with cell proliferation in uterine cervix cancer (2009), J. Exp. Clin. Cancer Res., 28, 43-55.
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
medicine in HeLa cells, transketolase-like enzyme 1 mRNA is specifically overexpressed compared with normal human endocervical epithelial cells. After anti-transketolase-like enzyme 1 siRNA treatment, total transketolase activity is significantly reduced and cell proliferation is remarkably inhibited. In endocervical epithelia cells, total transketolase activity and cell proliferation have no significant differences after siRNA treatment Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P51854
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-

Source Tissue

Source Tissue Comment Organism Textmining
epithelial cell
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 Homo sapiens
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HeLa cell
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 Homo sapiens
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Synonyms

Synonyms Comment Organism
transketolase-like enzyme 1
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens in HeLa cells, transketolase-like enzyme 1 mRNA is specifically overexpressed compared with normal human endocervical epithelial cells up

General Information

General Information Comment Organism
physiological function after anti-transketolase-like enzyme 1 siRNA treatment in HeLa cells, total transketolase activity is significantly reduced and cell proliferation is remarkably inhibited. In endocervical epithelia cells, total transketolase activity and cell proliferation have no significant differences after siRNA treatment Homo sapiens