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Literature summary for 2.10.1.1 extracted from

  • Llamas, A.; Otte, T.; Multhaup, G.; Mendel, R.R.; Schwarz, G.
    The Mechanism of nucleotide-assisted molybdenum insertion into molybdopterin. A novel route toward metal cofactor assembly (2006), J. Biol. Chem., 281, 18343-18350.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
sulfate less efficient inhibition than tungstate Arabidopsis thaliana
tungstate 20fold excess to molybdate Arabidopsis thaliana

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Arabidopsis thaliana
Mn2+ required, less efficient Arabidopsis thaliana
Ni2+ required, less efficient Arabidopsis thaliana
Zn2+ required Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
adenylyl-molybdopterin + molybdate + 4 H+ Arabidopsis thaliana
-
molybdenum cofactor + AMP + H2O
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q39054 domain E
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
adenylyl-molybdopterin + molybdate + 4 H+
-
Arabidopsis thaliana molybdenum cofactor + AMP + H2O
-
?

Synonyms

Synonyms Comment Organism
Cnx1 N-terminal E-domain, gene name Arabidopsis thaliana

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.25
-
molybdate in presence of Mg2+, pH 7.2, temperature not specified in the publication Arabidopsis thaliana
2.5
-
molybdate in presence of Zn2+, pH 7.2, temperature not specified in the publication Arabidopsis thaliana

General Information

General Information Comment Organism
metabolism molybdenum cofactor biosynthesis Arabidopsis thaliana