Literature summary for 2.10.1.1 extracted from

Nichols, J.D.; Rajagopalan, K.V.
In vitro molybdenum ligation to molybdopterin using purified components (2005), J. Biol. Chem., 280, 7817-7822.

Search for more literature for 2.10.1.1

Activating Compound

Activating Compound	Comment	Organism	Structure
molybdopterin adenylyltransferase	in presence of Mg2+ and ATP	Escherichia coli

Inhibitors

Inhibitors	Comment	Organism	Structure
glutathione	50% inhibition at 0.4 mM	Escherichia coli
L-cysteine	50% inhibition at 0.01 mM	Escherichia coli
molybdopterin adenylyltransferase	in absence of Mg2+ and ATP	Escherichia coli
Na2S	50% inhibition at 1.3 mM	Escherichia coli
tungstate	50% inhibition with 75 excess of tungstate	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
adenylyl-molybdopterin + molybdate + 4 H+	Escherichia coli	-	molybdenum cofactor + AMP + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	P12281	K-12	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
adenylyl-molybdopterin + molybdate + 4 H+	-	Escherichia coli	molybdenum cofactor + AMP + H2O	-	?

Synonyms

Synonyms	Comment	Organism
MoeA	-	Escherichia coli

General Information

General Information	Comment	Organism
metabolism	molybdenum cofactor biosynthesis	Escherichia coli

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Release 2023.1 (January 2023)