Application | Comment | Organism |
---|---|---|
medicine | presence of the enzyme in serum or urine may prove useful in development of kidney disease diagnosis, hyperornithinemia, an autosomal recessive disease caused by decreased enzyme activity, enzyme activity is also dimished in thyrotoxicosis and myotonic muscular dystrophy | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ornithine | competitive inhibition | Homo sapiens | |
ornithine | competitive inhibition | Rattus norvegicus | |
ornithine | - |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
2.27 | - |
arginine | - |
Sus scrofa | |
9.21 | - |
arginine | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Gallus gallus | 5739 | - |
mitochondrion | - |
Sus scrofa | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + glycine | Gallus gallus | - |
L-ornithine + guanidinoacetate | - |
r | |
L-arginine + glycine | Homo sapiens | - |
L-ornithine + guanidinoacetate | - |
r | |
L-arginine + glycine | Rattus norvegicus | - |
L-ornithine + guanidinoacetate | - |
r | |
L-arginine + glycine | Sus scrofa | - |
L-ornithine + guanidinoacetate | - |
r | |
L-arginine + glycine | Rattus norvegicus Sprague-Dawley | - |
L-ornithine + guanidinoacetate | - |
r | |
L-ornithine + guanidinoacetate | Gallus gallus | - |
L-arginine + glycine | - |
r | |
L-ornithine + guanidinoacetate | Sus scrofa | - |
L-arginine + glycine | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
chicken | - |
Homo sapiens | - |
human | - |
Rattus norvegicus | - |
- |
- |
Rattus norvegicus | - |
rat | - |
Rattus norvegicus Sprague-Dawley | - |
- |
- |
Sus scrofa | - |
pig, porcine, hog | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
brain | - |
Rattus norvegicus | - |
brain | - |
Sus scrofa | - |
fibroblast | - |
Homo sapiens | - |
kidney | - |
Gallus gallus | - |
kidney | - |
Sus scrofa | - |
liver | - |
Gallus gallus | - |
liver | - |
Sus scrofa | - |
lymphocyte | - |
Homo sapiens | - |
muscle | - |
Sus scrofa | - |
pancreas | - |
Gallus gallus | - |
pancreas | - |
Sus scrofa | - |
Storage Stability | Organism |
---|---|
-18°C, homogenized tissues stored during 1 month without any loss of enzyme activity | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
canavanine + ornithine | - |
Gallus gallus | arginine + canaline | - |
r | |
canavanine + ornithine | - |
Homo sapiens | arginine + canaline | - |
r | |
canavanine + ornithine | - |
Rattus norvegicus | arginine + canaline | - |
r | |
canavanine + ornithine | - |
Sus scrofa | arginine + canaline | - |
r | |
canavanine + ornithine | - |
Rattus norvegicus Sprague-Dawley | arginine + canaline | - |
r | |
L-arginine + glycine | - |
Gallus gallus | L-ornithine + guanidinoacetate | - |
r | |
L-arginine + glycine | - |
Homo sapiens | L-ornithine + guanidinoacetate | - |
r | |
L-arginine + glycine | - |
Rattus norvegicus | L-ornithine + guanidinoacetate | - |
r | |
L-arginine + glycine | - |
Sus scrofa | L-ornithine + guanidinoacetate | - |
r | |
L-arginine + glycine | - |
Rattus norvegicus Sprague-Dawley | L-ornithine + guanidinoacetate | - |
r | |
L-ornithine + guanidinoacetate | - |
Gallus gallus | L-arginine + glycine | - |
r | |
L-ornithine + guanidinoacetate | - |
Sus scrofa | L-arginine + glycine | - |
r |