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Literature summary for 2.1.2.9 extracted from

  • Nilsson, A.I.; Zorzet, A.; Kanth, A.; Dahlstroem, S.; Berg, O.G.; Andersson, D.I.
    Reducing the fitness cost of antibiotic resistance by amplification of initiator tRNA genes (2006), Proc. Natl. Acad. Sci. USA, 103, 6976-6981.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Salmonella enterica resistance mutations are identified in the fmt gene encoding the enzyme methionyl-tRNA formyltransferase. In the absence of antibiotic, these resistance mutations confer a fitness cost that is manifested as a reduced growth rate in laboratory medium and in mice ?
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Organism

Organism UniProt Comment Textmining
Salmonella enterica
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information resistance mutations are identified in the fmt gene encoding the enzyme methionyl-tRNA formyltransferase. In the absence of antibiotic, these resistance mutations confer a fitness cost that is manifested as a reduced growth rate in laboratory medium and in mice Salmonella enterica ?
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