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Literature summary for 2.1.2.7 extracted from

  • Wilson, E.M.; Snell, E.E.
    Metabolism of alpha-methylserine. II. Stereospecificity of alpha-methylserine hydroxymethyltransferase (1962), J. Biol. Chem., 237, 3180-3184.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Pseudomonas sp.
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
tetrahydrofolate + (+)-2-methylserine stereospecific, dimedon cannot replace tetrahydrofolate Pseudomonas sp. 5,10-methylenetetrahydrofolate + D-alanine + H2O
-
r
tetrahydrofolate + (-)-ethylserine stereospecific Pseudomonas sp. 5,10-methylenetetrahydrofolate + D-2-aminobutyrate + H2O
-
r
tetrahydrofolate + 2-hydroxymethylserine specific removal of one of the two hydroxyl groups Pseudomonas sp. 5,10-methylenetetrahydrofolate + D-serine + H2O
-
r

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate requirement Pseudomonas sp.