Literature summary for 2.1.2.2 extracted from

Liu, X.; Ding, Z.; Liu, Y.; Zhang, J.; Liu, F.; Wang, X.; He, X.; Cui, G.; Wang, D.
Glycinamide ribonucleotide formyl transferase is frequently overexpressed in glioma and critically regulates the proliferation of glioma cells (2014), Pathol. Res. Pract., 210, 256-263 .

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Application

Application	Comment	Organism
medicine	high GART expression is observed in glioma and is related to the grade of malignancy. GART overexpression is significantly associated with overall survival. Transfecting cells with GART-siRNA suppresses proliferation and enhances temozolomide-induced apoptosis in glioma cells	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P22102	enzymes displays phosphoribosylamine-glycine ligase activity, phosphoribosylformylglycinamidine cyclo-ligase activity and phosphoribosylglycinamide formyltransferase activity, cf. EC 6.3.4.13	-

Synonyms

Synonyms	Comment	Organism
GART	-	Homo sapiens
trifunctional purine biosynthetic protein adenosine-3	-	Homo sapiens

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Release 2023.1 (January 2023)