Literature summary for 2.1.2.2 extracted from

Stura, E.A.; Johnson, D.L; Inglese, J.; Smith, J.M.; Benkovic, S.J.; Wilson, I.A.
Preliminary crystallographic investigations of glycinamide ribonucleotide transformylase (1989), J. Biol. Chem., 264, 9703-9706.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Escherichia coli

Crystallization (Commentary)

Crystallization (Comment)	Organism
orthorhombic space group C222, a = 141.4 A, b = 98.2 A, c = 103.5 A	Escherichia coli

Inhibitors

Inhibitors	Comment	Organism	Structure
5,8-Dideazafolate	-	Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
23000	-	-	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide	Escherichia coli	essential enzyme in DNA synthesis, third enzyme in de novo purine biosynthesis pathway	tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide	-	Escherichia coli	tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide	-	?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide	essential enzyme in DNA synthesis, third enzyme in de novo purine biosynthesis pathway	Escherichia coli	tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide	-	?

Subunits

Subunits	Comment	Organism
monomer	1 * 23000	Escherichia coli

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Release 2023.1 (January 2023)