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Literature summary for 2.1.2.1 extracted from

  • Waditee-Sirisattha, R.; Kageyama, H.; Tanaka, Y.; Fukaya, M.; Takabe, T.
    Overexpression of halophilic serine hydroxymethyltransferase in fresh water cyanobacterium Synechococcus elongatus PCC7942 results in increased enzyme activities of serine biosynthetic pathways and enhanced salinity tolerance (2017), Arch. Microbiol., 199, 29-35 .
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in Synechococcus elongatus strain PCC7942 Aphanothece halophytica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5,10-methylenetetrahydrofolate + glycine + H2O Aphanothece halophytica
-
 tetrahydrofolate + L-serine
-
 r
tetrahydrofolate + L-serine Aphanothece halophytica
-
 5,10-methylenetetrahydrofolate + glycine + H2O
-
 r

Organism

Organism UniProt Comment Textmining
Aphanothece halophytica
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5,10-methylenetetrahydrofolate + glycine + H2O
-
 Aphanothece halophytica tetrahydrofolate + L-serine
-
 r
tetrahydrofolate + L-serine
-
 Aphanothece halophytica 5,10-methylenetetrahydrofolate + glycine + H2O
-
 r

Synonyms

Synonyms Comment Organism
serine hydroxymethyltransferase
-
 Aphanothece halophytica
SHMT
-
 Aphanothece halophytica

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate dependent on Aphanothece halophytica

General Information

General Information Comment Organism
physiological function Synechococcus elongatus PCC7942 cells expressing the enzyme from Aphanothece halophytica reveal an increase in growth under salt stress condition Aphanothece halophytica