Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.1.1.B125 extracted from

  • Lee, K.W.; Bogenhagen, D.F.
    Assignment of 2'-O-methyltransferases to modification sites on the mammalian mitochondrial large subunit 16 S ribosomal RNA (rRNA) (2014), J. Biol. Chem., 289, 24936-24942 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.B125

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
guanine1145 in 16S rRNA + S-adenosyl-L-methionine Homo sapiens
-
 2'-O-methylguanine1145 in 16S rRNA + S-adenosyl-L-homocysteine
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q6IN84
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
-
 Homo sapiens
-
HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
guanine1145 in 16S rRNA + S-adenosyl-L-methionine
-
 Homo sapiens 2'-O-methylguanine1145 in 16S rRNA + S-adenosyl-L-homocysteine
-
 ?

Synonyms

Synonyms Comment Organism
MRM1
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function knockdown of MRM1 significantly increases accessibility of 16 S rRNA to DNAzyme cleavage at residue G1145 Homo sapiens