Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.1.1.85 extracted from

  • Kwiatkowski, S.; Seliga, A.K.; Vertommen, D.; Terreri, M.; Ishikawa, T.; Grabowska, I.; Tiebe, M.; Teleman, A.A.; Jagielski, A.K.; Veiga-da-Cunha, M.; Drozak, J.
    SETD3 protein is the actin-specific histidine N-methyltransferase (2018), eLife, 7, e37921 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.85

Cloned(Commentary)

Cloned (Comment) Organism
expressed in COS-7 cells, HAP-1 cells and HEK-293T cells Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + protein L-histidine73 Rattus norvegicus
-
 S-adenosyl-L-homocysteine + protein Ntau-methyl-L-histidine73
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
DEAE-Sepharose column chromatography, Q-Sepharose column chromatography, phenyl Sepharose column chromatography, HiScreen Blue Sepharose column chromatography, Reactive Red 120 agarose column chromatography, and Superdex S200 gel filtration Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no activity with human beta-actin mutant H73A, ATP-bound actin or ADP-bound actin Rattus norvegicus ?
-
-
S-adenosyl-L-methionine + human beta-actin L-histidine73
-
 Rattus norvegicus S-adenosyl-L-homocysteine + protein Ntau-methyl-L-histidine73
-
 ?
S-adenosyl-L-methionine + protein L-histidine73
-
 Rattus norvegicus S-adenosyl-L-homocysteine + protein Ntau-methyl-L-histidine73
-
 ?

Subunits

Subunits Comment Organism
? x * 70000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
actin-specific histidine N-methyltransferase
-
 Rattus norvegicus
setd3
-
 Rattus norvegicus