Literature summary for 2.1.1.77 extracted from

Kindrachuk, J.; Parent, J.; Davies, G.F.; Dinsmore, M.; Attah-Poku, S.; Napper, S.
Overexpression of L-isoaspartate O-methyltransferase in Escherichia coli increases heat shock survival by a mechanism independent of methyltransferase activity (2003), J. Biol. Chem., 278, 50880-50886.

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Cloned(Commentary)

Cloned (Comment)	Organism
overexpression of the enzyme in Escherichia coli increases heat shock survival by a mechanism independent of methyltransferase activity	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
S-adenosyl-L-methionine + protein L-isoaspartate	Escherichia coli	the enzyme prevents the accumulation of deaminated proteins	S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + protein L-isoaspartate	the enzyme prevents the accumulation of deaminated proteins	Escherichia coli	S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester	-	?

Synonyms

Synonyms	Comment	Organism
L-isoaspartate O-methyltransferase	-	Escherichia coli
PIMT	-	Escherichia coli

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Release 2023.1 (January 2023)