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Literature summary for 2.1.1.72 extracted from

  • Sun, K.; Jiao, X.D.; Zhang, M.; Sun, L.
    DNA adenine methylase is involved in the pathogenesis of Edwardsiella tarda (2010), Vet. Microbiol., 141, 149-154.
    View publication on PubMed
Search for more literature for 2.1.1.72

Cloned(Commentary)

Cloned (Comment) Organism
expressed in dam-deficient Escherichia coli strain ER2925 Edwardsiella tarda

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + DNA adenine Edwardsiella tarda Dam catalyzes the methylation of N-6 of the adenine residue in GATC sequences S-adenosyl-L-homocysteine + DNA 6-methyladenine
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 ?
S-adenosyl-L-methionine + DNA adenine Edwardsiella tarda TXD1 Dam catalyzes the methylation of N-6 of the adenine residue in GATC sequences S-adenosyl-L-homocysteine + DNA 6-methyladenine
-
 ?

Organism

Organism UniProt Comment Textmining
Edwardsiella tarda D5FM16
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Edwardsiella tarda TXD1 D5FM16
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + DNA adenine Dam catalyzes the methylation of N-6 of the adenine residue in GATC sequences Edwardsiella tarda S-adenosyl-L-homocysteine + DNA 6-methyladenine
-
 ?
S-adenosyl-L-methionine + DNA adenine Dam catalyzes the methylation of N-6 of the adenine residue in GATC sequences Edwardsiella tarda TXD1 S-adenosyl-L-homocysteine + DNA 6-methyladenine
-
 ?

Synonyms

Synonyms Comment Organism
Dam
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 Edwardsiella tarda
DNA adenine methyltransferase
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 Edwardsiella tarda

General Information

General Information Comment Organism
physiological function Dam is a virulence determinant and plays a role in the pathogenesis of Edwardiella tarda strain TXD1, temporal expression of dam is essential for optimal bacterial infection Edwardsiella tarda