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Literature summary for 2.1.1.72 extracted from

  • Kossykh, V.G.; Lloyd, R.S.
    A DNA adenine methyltransferase of Escherichia coli that is cell cycle regulated and essential for viability (2004), J. Bacteriol., 186, 2061-2067.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.72

Cloned(Commentary)

Cloned (Comment) Organism
gene yhdJ or ccrM, chromosomally encoded, DNA sequence determination and analysis, overvexpression decreases bacterial growth by altering cell division, cells show aberant morphology Escherichia coli

Protein Variants

Protein Variants Comment Organism
additional information construction of a ccrM null mutant Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + DNA adenine Escherichia coli the enzyme is cell cycle regulated and essential for viability S-adenosyl-L-homocysteine + DNA 6-methylaminopurine
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
 gene yhdJ or ccrM
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme from overexpression Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + DNA adenine the enzyme is cell cycle regulated and essential for viability Escherichia coli S-adenosyl-L-homocysteine + DNA 6-methylaminopurine
-
 ?
S-adenosyl-L-methionine + DNA adenine enzyme methylates the first adenine in the sequence ATGCAT Escherichia coli S-adenosyl-L-homocysteine + DNA 6-methylaminopurine
-
 ?

Synonyms

Synonyms Comment Organism
CcrM DNA adenine methyltransferase
-
 Escherichia coli
cell cycle-regulated methyltransferase
-
 Escherichia coli
DNA adenine methyltransferase
-
 Escherichia coli
DNA MTase
-
 Escherichia coli
M.EcoKCcrM
-
 Escherichia coli