Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Co2+ | - |
Ruta graveolens | |
Cu2+ | - |
Ruta graveolens | |
Fe2+ | - |
Ruta graveolens | |
kinetin | strong inhibition | Ruta graveolens | |
Mg2+ | slightly inhibits the O-methylation of bergaptol | Ruta graveolens | |
Ni2+ | - |
Ruta graveolens | |
p-chloromercuribenzoic acid | - |
Ruta graveolens | |
Zn2+ | - |
Ruta graveolens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
110000 | - |
gel filtration | Ruta graveolens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + bergaptol | Ruta graveolens | furanocoumarinbiosynthesis | S-adenosyl-L-homocysteine + bergapten | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Heracleum maximum | - |
Michx. | - |
Heracleum maximum Michx. | - |
Michx. | - |
Ruta graveolens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | - |
Heracleum maximum | - |
leaf | sterile leaf cell culture | Ruta graveolens | - |
shoot | young shoots of field-grown plants | Ruta graveolens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.000029 | - |
bergaptol | Ruta graveolens |
0.000056 | - |
5-hydroxyxanthotoxin | Ruta graveolens |
Storage Stability | Organism |
---|---|
-20°C, stored and refrozen, activity against bergaptol is essentially unchanged after 18 days and is still 65% of the initial value after 34 days | Ruta graveolens |
0°C, stored below undesalted, 40% loss of activity after 5 weeks | Ruta graveolens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | activity against phenol, resorcinol, phloroglucinol, 3-hydroxy-4-methoxybenzaldehyde, 2-hydroxybenzoic acid, 3-hydroxybenzoic acid, 2-hydroxyphenylacetic acid, 3-hydroxycinnamic acid, and quercetin-7,4'-dimethyl ether lower than 10% of the activity observed with bergaptol as substrate | Ruta graveolens | ? | - |
? | |
S-adenosyl-L-methionine + 5-hydroxyxanthotoxin | - |
Ruta graveolens | S-adenosyl-L-homocysteine + isopimpinellin | - |
? | |
S-adenosyl-L-methionine + 5-hydroxyxanthotoxin | - |
Heracleum maximum | S-adenosyl-L-homocysteine + isopimpinellin | - |
? | |
S-adenosyl-L-methionine + 5-hydroxyxanthotoxin | - |
Heracleum maximum Michx. | S-adenosyl-L-homocysteine + isopimpinellin | - |
? | |
S-adenosyl-L-methionine + bergaptol | - |
Ruta graveolens | S-adenosyl-L-homocysteine + bergapten | - |
? | |
S-adenosyl-L-methionine + bergaptol | - |
Heracleum maximum | S-adenosyl-L-homocysteine + bergapten | - |
? | |
S-adenosyl-L-methionine + bergaptol | furanocoumarinbiosynthesis | Ruta graveolens | S-adenosyl-L-homocysteine + bergapten | - |
? | |
S-adenosyl-L-methionine + bergaptol | - |
Heracleum maximum Michx. | S-adenosyl-L-homocysteine + bergapten | - |
? | |
S-adenosyl-L-methionine + caffeic acid | - |
Ruta graveolens | S-adenosyl-L-homocysteine + ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.3 | 8 | - |
Ruta graveolens |
8.5 | 9 | 5-hydroxyanthotoxin as substrate | Ruta graveolens |