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Literature summary for 2.1.1.67 extracted from
- Glutathione: an endogenous substrate for thiopurine methyltransferase? (1985), Biochem. Biophys. Res. Commun., 126, 1201-1207.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| glutathione | - |
Rattus norvegicus |  |
| S-Methylglutathione | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus norvegicus | 5829 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + a thiopurine | Rattus norvegicus | - |
S-adenosyl-L-homocysteine + a thiopurine S-methylether | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
rat, Sprague-Dawley | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | glutathione is no substrate | Rattus norvegicus | ? | - |
? | |
| S-adenosyl-L-methionine + 6-thiopurine | - |
Rattus norvegicus | S-adenosyl-L-homocysteine + 6-methylthiopurine | - |
? | |
| S-adenosyl-L-methionine + a thiopurine | - |
Rattus norvegicus | S-adenosyl-L-homocysteine + a thiopurine S-methylether | - |
? | |
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