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Literature summary for 2.1.1.63 extracted from

  • Hu, J.; Ma, A.; Dinner, A.R.
    A two-step nucleotide-flipping mechanism enables kinetic discrimination of DNA lesions by AGT (2008), Proc. Natl. Acad. Sci. USA, 105, 4615-4620.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA (containing 6-O-methylguanine) + [protein]-L-cysteine Homo sapiens
-
DNA (without 6-O-methylguanine) + [protein]-S-methyl-L-cysteine
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P16455
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA (containing 6-O-methylguanine) + [protein]-L-cysteine
-
Homo sapiens DNA (without 6-O-methylguanine) + [protein]-S-methyl-L-cysteine
-
?

Synonyms

Synonyms Comment Organism
AGT
-
Homo sapiens
O6-alkylguanine-DNA alkyltransferase
-
Homo sapiens