Literature summary for 2.1.1.56 extracted from

Selisko, B.; Peyrane, F.F.; Canard, B.; Alvarez, K.; Decroly, E.
Biochemical characterization of the (nucleoside-2'O)-methyltransferase activity of dengue virus protein NS5 using purified capped RNA oligonucleotides (7Me)GpppAC(n) and GpppAC(n) (2010), J. Gen. Virol., 91, 112-121.

Search for more literature for 2.1.1.56

Inhibitors

Inhibitors	Comment	Organism	Structure
sinefungin	-	Dengue virus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
S-adenosyl-L-methionine + G(5')pppR-RNA	Dengue virus	-	S-adenosyl-L-homocysteine + m7G(5')pppR-RNA	-	?

Organism

Organism	UniProt	Comment	Textmining
Dengue virus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + G(5')pppR-RNA	-	Dengue virus	S-adenosyl-L-homocysteine + m7G(5')pppR-RNA	-	?

Synonyms

Synonyms	Comment	Organism
mRNA cap (guanine N-7) methyltransferase	part of the NS5 protein	Dengue virus
mRNA cap (guanine N-7) MTase	part of the NS5 protein	Dengue virus
nonstructural protein 5 methyltransferase	-	Dengue virus
NS5MTase	the protein contains mRNA cap (guanine N-7) methyltransferase and (nucleoside-2'O)-methyltransferase activities	Dengue virus

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Release 2023.1 (January 2023)