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Literature summary for 2.1.1.45 extracted from

  • Leclerc, G.J.; Mou, C.; Leclerc, G.M.; Mian, A.M.; Barredo, J.C.
    Histone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood acute lymphoblastic leukemia: implications for combination therapy (2010), Leukemia, 24, 552-562.
    View publication on PubMed

Application

Application Comment Organism
medicine target for therapy of acute lymphoblastic leukemia Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cell nucleus
-
Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
CCRF-CEM cell
-
Homo sapiens
-
NALM-6 cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
thymidylate synthetase
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens decreased mRNA expression after treatment with sodium butyrate or suberoylanilide hydroxamic acid down