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Literature summary for 2.1.1.45 extracted from

  • Leduc, D.; Graziani, S.; Meslet-Cladiere, L.; Sodolescu, A.; Liebl, U.; Myllykallio, H.
    Two distinct pathways for thymidylate (dTMP) synthesis in (hyper)thermophilic bacteria and archaea (2004), Biochem. Soc. Trans., 32, 231-235.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Archaeoglobus fulgidus
-
-
-
Methanocaldococcus jannaschii
-
-
-
Methanopyrus kandleri
-
AV19
-
Methanothermobacter thermautotrophicus
-
-
-
no activity in Aeropyrum pernix
-
-
-
no activity in Aquifex aeolicus
-
-
-
no activity in Pyrobaculum aerophilum
-
-
-
no activity in Pyrococcus abyssi
-
-
-
no activity in Pyrococcus furiosus
-
DSM 3638
-
no activity in Pyrococcus horikoshii
-
-
-
no activity in Sulfolobus solfataricus
-
-
-
no activity in Sulfolobus tokodaii
-
-
-
no activity in Thermoplasma acidophilum
-
-
-
no activity in Thermoplasma volcanium
-
-
-
no activity in Thermotoga maritima
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5,10-methylenetetrahydrofolate + dUMP
-
Methanothermobacter thermautotrophicus dihydrofolate + dTMP
-
?
5,10-methylenetetrahydrofolate + dUMP
-
Methanocaldococcus jannaschii dihydrofolate + dTMP
-
?
5,10-methylenetetrahydrofolate + dUMP
-
Archaeoglobus fulgidus dihydrofolate + dTMP
-
?
5,10-methylenetetrahydrofolate + dUMP
-
Methanopyrus kandleri dihydrofolate + dTMP
-
?

Synonyms

Synonyms Comment Organism
ThyA
-
Methanothermobacter thermautotrophicus
ThyA
-
Methanocaldococcus jannaschii
ThyA
-
Archaeoglobus fulgidus
ThyA
-
Methanopyrus kandleri