Literature summary for 2.1.1.41 extracted from

Oelschlager, A.C.; Angus, R.H.; Pierce, A.M.; Pierce, H.D.; Srinivasan, R.
Azasterol inhibition of delta 24-sterol methyltransferase in Saccharomyces cerevisiae (1984), Biochemistry, 23, 3582-3589.

Search for more literature for 2.1.1.41

Inhibitors

Inhibitors	Comment	Organism	Structure
22,25-Diazacholesterol	20R and 20S isomer	Saccharomyces cerevisiae
23-Azacholesterol	-	Saccharomyces cerevisiae
24-Azacholesterol	-	Saccharomyces cerevisiae
25-aza-24,25-dihydrolanosterol	-	Saccharomyces cerevisiae
25-Aza-24,25-dihydrozymosterol	-	Saccharomyces cerevisiae
25-Azacholestanol	-	Saccharomyces cerevisiae
25-Azacholesterol	-	Saccharomyces cerevisiae
25-Azacholesterol hydrochloride	-	Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
zymosterol + S-adenosyl-L-methionine	Saccharomyces cerevisiae	-	fecosterol + S-adenosyl-L-homocysteine	-	?

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
zymosterol + S-adenosyl-L-methionine	-	Saccharomyces cerevisiae	fecosterol + S-adenosyl-L-homocysteine	-	?
zymosterol + S-adenosyl-L-methionine	zymosterol is 5alpha-cholesta-8,24-dien-3beta-ol	Saccharomyces cerevisiae	fecosterol + S-adenosyl-L-homocysteine	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.00000125	-	25-Aza-24,25-dihydrozymosterol	-	Saccharomyces cerevisiae

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)