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Literature summary for 2.1.1.361 extracted from

  • Wang, C.; Wu, J.; Zhao, Y.; Guo, Z.
    MiR-502 mediated histone methyltransferase SET8 expression is associated with outcome of esophageal squamous cell carcinoma (2016), Sci. Rep., 6, 32921 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.361

Application

Application Comment Organism
medicine enzyme knockdown can inhibit proliferation and promote apoptosis of esophageal squamous cell carcinoma cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + a [histone H4]-L-lysine20 Homo sapiens
-
 S-adenosyl-L-homocysteine + a [histone H4]-N6-methyl-L-lysine20
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9NQR1
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Eca-109 cell
-
 Homo sapiens
-
esophageal squamous cell carcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + a [histone H4]-L-lysine20
-
 Homo sapiens S-adenosyl-L-homocysteine + a [histone H4]-N6-methyl-L-lysine20
-
 ?

Synonyms

Synonyms Comment Organism
SET8
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction enzyme knockdown inhibits proliferation, induces apoptosis, suppresses migration and invasion of esophageal squamous cell carcinoma cells Homo sapiens