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Literature summary for 2.1.1.361 extracted from

  • Spektor, T.M.; Congdon, L.M.; Veerappan, C.S.; Rice, J.C.
    The UBC9 E2 SUMO conjugating enzyme binds the PR-Set7 histone methyltransferase to facilitate target gene repression (2011), PLoS ONE, 6, e22785 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.361

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleosome
-
 Homo sapiens 786
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + a [histone H4]-L-lysine20 Homo sapiens
-
 S-adenosyl-L-homocysteine + a [histone H4]-N6-methyl-L-lysine20
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9NQR1
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme interacts with the UBC9 E2 SUMO conjugating enzyme and is preferentially modified with SUMO1 in vivo Homo sapiens ?
-
 ?
S-adenosyl-L-methionine + a [histone H4]-L-lysine20
-
 Homo sapiens S-adenosyl-L-homocysteine + a [histone H4]-N6-methyl-L-lysine20
-
 ?

Subunits

Subunits Comment Organism
? x * 50000, His-S-tagged enzyme, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
KMT5a
-
 Homo sapiens
Pr-Set7
-
 Homo sapiens
SET8
-
 Homo sapiens