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Literature summary for 2.1.1.361 extracted from

  • Zouaz, A.; Fernando, C.; Perez, Y.; Sardet, C.; Julien, E.; Grimaud, C.
    Cell-cycle regulation of non-enzymatic functions of the Drosophila methyltransferase PR-Set7 (2018), Nucleic Acids Res., 46, 2834-2849 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.361

Cloned(Commentary)

Cloned (Comment) Organism
expressed in S2 cells Drosophila melanogaster

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleosome
-
 Drosophila melanogaster 786
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Drosophila melanogaster the proteolytic degradation of the enzyme is controlled by the SCFSlimb ligase complex ?
-
 ?
S-adenosyl-L-methionine + a [histone H4]-L-lysine20 Drosophila melanogaster
-
 S-adenosyl-L-homocysteine + a [histone H4]-N6-methyl-L-lysine20
-
 ?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster Q9VFK6
-
-

Purification (Commentary)

Purification (Comment) Organism
phosphoprotein column chromatography Drosophila melanogaster

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the proteolytic degradation of the enzyme is controlled by the SCFSlimb ligase complex Drosophila melanogaster ?
-
 ?
S-adenosyl-L-methionine + a [histone H4]-L-lysine20
-
 Drosophila melanogaster S-adenosyl-L-homocysteine + a [histone H4]-N6-methyl-L-lysine20
-
 ?

Subunits

Subunits Comment Organism
? x * 100000, SDS-PAGE Drosophila melanogaster

Synonyms

Synonyms Comment Organism
histone H4-K20 methyltransferase
-
 Drosophila melanogaster
KMT5a
-
 Drosophila melanogaster
Pr-Set7
-
 Drosophila melanogaster
SET8
-
 Drosophila melanogaster
SETD8
-
 Drosophila melanogaster

General Information

General Information Comment Organism
physiological function Slimb-mediated enzyme proteolysis is a critical regulatory mechanism required for proper interphase chromatin organization at G1/S transition Drosophila melanogaster