Any feedback?
Literature summary for 2.1.1.354 extracted from
- Histone H3 lysine 4 trimethylation regulates cotranscriptional H2A variant exchange by Tip60 complexes to maximize gene expression (2014), Proc. Natl. Acad. Sci. USA, 111, 4850-4855.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Drosophila melanogaster | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + histone H3(K4) | - |
Drosophila melanogaster | S-adenosyl-L-homocysteine + N-methylated histone H3(K4) | - |
? |  |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | histone H3 lysine 4 trimethylation by isoform Set1 regulates both the acetylated histone variant H2A.Z/v exchange and histone acetyltransferase activities of Tip60 complexes to ensure that nucleosome destabilization at promoters only occurs during transcription | Drosophila melanogaster |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
