Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.1.1.354 extracted from

  • Hallson, G.; Hollebakken, R.E.; Li, T.; Syrzycka, M.; Kim, I.; Cotsworth, S.; Fitzpatrick, K.A.; Sinclair, D.A.; Honda, B.M.
    dSet1 is the main H3K4 di- and tri-methyltransferase throughout Drosophila development (2012), Genetics, 190, 91-100.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.354

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
larva
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + histone H3(K4)
-
 Drosophila melanogaster ?
-
 ?

Synonyms

Synonyms Comment Organism
dSet1
-
 Drosophila melanogaster
H3K4 HMT
-
 Drosophila melanogaster
H3K4 methyltransferase
-
 Drosophila melanogaster

General Information

General Information Comment Organism
malfunction histone H3(K4) di- and trimethylations are significantly reduced in dSet1 mutants during late larval und post-larval stages Drosophila melanogaster
physiological function dSet1 is the main histone H3(K4) di- and tri-methyltransferase throughout Drosophila development. dSet1 interacts with members of a putative Drosophila COMPASS (complex of proteins associated with Set1) which is functionally required for histone H3(K4) methylation Drosophila melanogaster