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Literature summary for 2.1.1.354 extracted from
- A mouse speciation gene encodes a meiotic histone H3 methyltransferase (2009), Science, 323, 373-375.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | C4MLH8 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| ovary | - |
Mus musculus | - |
| testis | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + histone H3(K4) | - |
Mus musculus | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| H3K4 trimethyltransferase | - |
Mus musculus |
| histone H3 lysine 4 trimethyltransferase | - |
Mus musculus |
| Hst1 | - |
Mus musculus |
| hybrid sterility protein 1 | - |
Mus musculus |
| Prdm9 | - |
Mus musculus |
| Prdm9 | the Prdm9 gene is also known as Meisetz | Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | Prdm9-null mice show arrest of spermatogenesis and oogenesis at pachynema, impairment of double-strand break repair, chromosome asynapsis, and disrupted sex-body formation | Mus musculus |
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