Cloned (Comment) | Organism |
---|---|
expressed in Sf9 insect cells | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | - |
Homo sapiens | 5634 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + adenine in RNA | Homo sapiens | - |
S-adenosyl-L-homocysteine + N6-methyladenine in RNA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q86U44 | - |
- |
Homo sapiens | Q9HCE5 | - |
- |
Purification (Comment) | Organism |
---|---|
anti-Flag M2 affinity gel chromatography and Superdex S200 gel filtration | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme preferentially methylates substrates containing the consensus sequence Pu[G>A]m6AC[U>A>C], but exhibit no obvious preference to the stem-loop structure for N6-methyladenine deposition | Homo sapiens | ? | - |
- |
|
S-adenosyl-L-methionine + adenine in RNA | - |
Homo sapiens | S-adenosyl-L-homocysteine + N6-methyladenine in RNA | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * about 70000, SDS-PAGE | Homo sapiens |
? | x * about 65000, METTL14, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
METTL14 | - |
Homo sapiens |
METTL3 | - |
Homo sapiens |
RNA m6A methyltransferase | - |
Homo sapiens |