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Literature summary for 2.1.1.33 extracted from

  • Alexandrov, A.; Chernyakov, I.; Gu, W.; Hiley, S.L.; Hughes, T.R.; Grayhack, E.J.; Phizicky, E.M.
    Rapid tRNA decay can result from lack of nonessential modifications (2006), Mol. Cell, 21, 87-96.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae Q03774 and Q12009 Q03774: subunit Trm82, Q2009: subunit Trm8
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Synonyms

Synonyms Comment Organism
m7G46 methyltransferase Trm8p/Trm82p
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Saccharomyces cerevisiae

General Information

General Information Comment Organism
malfunction absence of m7G46 results in temperature-sensitive growth Saccharomyces cerevisiae
physiological function m7G46 methyltransferase Trm8p/Trm82p acts as a hub of synthetic interactions with several tRNA modification enzymes, resulting in temperature-sensitive growth Saccharomyces cerevisiae