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Literature summary for 2.1.1.321 extracted from
- Epigenetic control via allosteric regulation of mammalian protein arginine methyltransferases (2017), Proc. Natl. Acad. Sci. USA, 114, 10101-10106 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + [histone H4R17]-L-arginine | Homo sapiens | PRMT7-mediated monomethylation of histone H4 Arg17 regulates PRMT5 activity at Arg3 in the same protein | S-adenosyl-L-homocysteine + [histone H4R17]-Nomega-methyl-L-arginine | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q9NVM4 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + [histone H4R17]-L-arginine | - |
Homo sapiens | S-adenosyl-L-homocysteine + [histone H4R17]-Nomega-methyl-L-arginine | - |
? | |
| S-adenosyl-L-methionine + [histone H4R17]-L-arginine | PRMT7-mediated monomethylation of histone H4 Arg17 regulates PRMT5 activity at Arg3 in the same protein | Homo sapiens | S-adenosyl-L-homocysteine + [histone H4R17]-Nomega-methyl-L-arginine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PRMT7 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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