Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + [eukaryotic translation initiation factor 2alpha]-L-arginine | Homo sapiens | PRMT7 methylates eukaryotic translation initiation factor 2alpha (eIF2alpha) and regulates its role in stress granule formation | S-adenosyl-L-homocysteine + [eukaryotic translation initiation factor 2alpha]-Nomega-methyl-L-arginine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9NVM4 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MCF-7 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + [eukaryotic translation initiation factor 2alpha]-L-arginine | PRMT7 methylates eukaryotic translation initiation factor 2alpha (eIF2alpha) and regulates its role in stress granule formation | Homo sapiens | S-adenosyl-L-homocysteine + [eukaryotic translation initiation factor 2alpha]-Nomega-methyl-L-arginine | - |
? | |
S-adenosyl-L-methionine + [eukaryotic translation initiation factor 2alpha]-L-arginine | PRMT7 methylates eukaryotic translation initiation factor 2alpha (eIF2alpha) within an RXR motif and regulates its role in stress granule formation | Homo sapiens | S-adenosyl-L-homocysteine + [eukaryotic translation initiation factor 2alpha]-Nomega-methyl-L-arginine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PRMT7 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | stress granule formation, in the face of eIF2alpha-dependent cellular stresses, is significantly diminished in PRMT7-knockdown | Homo sapiens |
physiological function | PRMT7 methylates eukaryotic translation initiation factor 2alpha and regulates its role in stress granule formation | Homo sapiens |